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| 13 May | | | | Chelsea | 2 - 1 | Blackburn | J Terry (30)
RJT Meireles (33) | | A Yakubu (59) |
| | Stamford Bridge | Attendance (40742) | | Teams | Report |
| | 13 May | | | | Everton | 3 - 1 | Newcastle | S Pienaar (15)
N Jelavic (26)
J Heitinga (65) | | T Hibbert (og 72) |
| | Goodison Park | Attendance (39517) | | Teams | Report |
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| 13 May | | | | Man City | 3 - 2 | QPR | PJ Zabaleta (38)
E Dzeko (90)
SL Aguero (90) | | D Cisse (47)
J Mackie (65) |
| | Etihad Stadium | | | Teams | Report |
| | 13 May | | | | Norwich | 2 - 0 | Aston Villa | | | Carrow Road | Attendance (26803) | | Teams | Report |
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| 13 May | | | | Tottenham | 2 - 0 | Fulham | E Adebayor (1)
J Defoe (62) | | |
| | White Hart Lane | Attendance (36256) | | Teams | Report |
| | 13 May | | | | Stoke | 2 - 2 | Bolton | J Walters (12)
J Walters (pen 76) | | M Davies (38)
KC Davies (44) |
| | Britannia Stadium | | | Teams | Report |
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| 13 May | | | | Sunderland | 0 - 1 | Man Utd | | | Stadium of Light | Attendance (46452) | | Teams | Report |
| | 13 May | | | | West Brom | 2 - 3 | Arsenal | S Long (10)
G Dorrans (14) | | Y Benayoun (3)
C Andre Santos (29)
L Koscielny (53) |
| | The Hawthorns | Attendance (26358) | | Teams | Report |
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| 13 May | | | | Swansea | 1 - 0 | Liverpool | | | Liberty Stadium | Attendance (20605) | | Teams |
| | 13 May | | | | Wigan | 3 - 2 | Wolverhampton | F Di Santo (11)
E Boyce (13)
E Boyce (78) | | M Jarvis (8)
S Fletcher (85) |
| | The DW Stadium | Attendance (21986) | | Teams | Report |
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| 08 May | | | | Liverpool | 4 - 1 | Chelsea | M Essien (og 18)
J Henderson (24)
D Agger (27)
J Shelvey (60) | | NS Ramires (49) |
| | Anfield | Attendance (40721) | | Teams | Report |
| | 07 May | | | | Blackburn | 0 - 1 | Wigan | | | Ewood Park | Attendance (26144) | | Teams | Report |
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| 06 May | | | | Man Utd | 2 - 0 | Swansea | P Scholes (27)
A Young (40) | | |
| | Old Trafford | Attendance (75496) | | Teams | Report |
| | 06 May | | | | QPR | 1 - 0 | Stoke | | | Loftus Road Stadium | Attendance (17319) | | Teams | Report |
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| 06 May | | | | Wolverhampton | 0 - 0 | Everton | | Molineux Stadium | Attendance (25466) | | Teams | Report |
| | 06 May | | | | Bolton | 2 - 2 | West Brom | M Petrov (pen 23)
B Jones (og 71) | | C Brunt (74)
J Morrison (89) |
| | Reebok Stadium | Attendance (25662) | | Teams | Report |
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| 06 May | | | | Fulham | 2 - 1 | Sunderland | CD Dempsey (11)
M Dembele (34) | | P Bardsley (33) |
| | Craven Cottage | Attendance (25683) | | Teams | Report |
| | 06 May | | | | Aston Villa | 1 - 1 | Tottenham | | C Clark (34) | | E Adebayor (pen 61) |
| | Villa Park | Attendance (36008) | | Teams | Report |
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| 06 May | | | | Newcastle | 0 - 2 | Man City | | | | G Toure Yaya (69)
G Toure Yaya (88) |
| | Sports Direct Arena | Attendance (52389) | | Teams | Report |
| | 05 May | | | | Arsenal | 3 - 3 | Norwich | Y Benayoun (1)
R van Persie (71)
R van Persie (79) | | W Hoolahan (11)
G Holt (26)
S Morison (84) |
| | Emirates Stadium | Attendance (60092) | | Teams | Report |
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| 02 May | | | | Bolton | 1 - 4 | Tottenham | | N Reo-Coker (50) | | L Modric (36)
R Van der Vaart (59)
E Adebayor (61)
E Adebayor (68) |
| | Reebok Stadium | Attendance (22349) | | Teams | Report |
| | 02 May | | | | Chelsea | 0 - 2 | Newcastle | | | Stamford Bridge | Attendance (41559) | | Teams |
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| 01 May | | | | Liverpool | 0 - 1 | Fulham | | | Anfield | Attendance (40106) | | Teams | Report |
| | 01 May | | | | Stoke | 1 - 1 | Everton | | C Jerome (68) | | P Crouch (og 44) |
| | Britannia Stadium | Attendance (26500) | | Teams | Report |
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